Gene: [13^/BCS1] breast cancer, ductal, suppressor 1; [BRCD1 BCDS1 ]


FAG

A gene with similar biological effect is located in chr 1 (GEM:01p36/BCS2). Inactivation of these genes, e.g. in the phenomenon of loss of heterozygosity, results in ductal brast cancer (BCS1) or breast-ovarian cancer (BCS2)."

HET

Other breast cancer types may be related to the following genes: GEM:01p36/BCS2; GEM:01q2/SKI; GEM:11p155/ADCR; GEM:21q223/TFF1."

REF

REV,PAT,MUT,FAG "Callahan, Campbell: J Nat Cancer Inst, 81, N23, 1780-1786, 1989
PAT,PHE,FOG "Fraumeni &: Cancer, 36, 364-369, 1975
LIN "Friend SH &: PNAS, 84, N24, 9059-9063, 1987
LOC,LIN,CYG "Lundberg &: PNAS, 84, N8, 2371-2376, 1987
PAT,PHE,FOG "Lynch &: Cancer, 41, 1543-1549, 1978
PAT,LIN,FAG "Rodgers CS &: Cancer Genet Cytogenet, 13, 95-119, 1984

KEY

onc, horm

CLA

unknown, basic

LOC

13

MIM

MIM: 211410

SYN

BRCD1 BCDS1